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ea0077p139 | Adrenal and Cardiovascular | SFEBES2021

The ULTRADIAN consortium - Ambulatory in vivo micro dialysis in primary adrenal insufficiency, preliminary data

Russell Georgina , Upton Thomas , Zavala Eder , Methlie Paal , Simunkova Katerina , Berinder Katerina , Botusan Ileena , Vassiliadi Dimitria , Tsagarakis Stelios , Kampe Olle , Husebye Eystein , Lightman Stafford , Oksnes Marianne , Bensing Sophie

Patients on long term glucocorticoid replacement therapy have higher rates of morbidity and mortality. One causative factor may be non-physiological cortisol replacement. We have developed as part of the ULTRADIAN consortium (https://www.uib.no/en/ultradian) the U-RHYTHM, an ambulatory bio-sampling device that can collect clinical samples using in-vivo microdialysis every 20 minutes over the 24hour day whilst individuals continue with their normal everyday activities....

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The ULTRADIAN consortium - Ambulatory in vivo micro dialysis in primary adrenal insufficiency, preliminary data

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